View Full Version : Problems with Compounded Prilosec


divertigozzy
09-23-2006, 05:20 PM
My son has been on 8 ml of 2mg/ml prilosec and it has been so inconsistent. We have had to have it filled at 2 different pharmacies and I can always tell right away when the prilosec is not compounded well. Last time I had the same pharmacist do the next bottle and it was almost clear while the old bottle was white in color (like it should be) ..immediately after starting the new bottle my sons reflux started back up very badly. I called the pharmacist and she said it was a very hard drug to compound.

Our Drs decided to switch us to prevacid to avoid the inconsistency but from what I read thats not going to help either. Either we go to compounded prevacid which I suspect we are going to have the same problems with or the solutab which we have been on for 5 days now and his reflux is worse then I have ever seen it..retching constantly. I would love to go back to the prilosec if I could find a way to make sure its consistent everytime..its hard enough finding anyone around here who compounds meds around here. Do you think it may take some more time for the solutab prevacids to kick in? I am not sure when to say enough is enough! Any advice would be great

Thanks!

Kristin

graham
09-26-2006, 07:06 AM
kristin, it sounds like you are having a hard time. The medications you are giving should be given about an hour to 1/2 hour before a meal (like breakfast); if not, you may not be getting maximum benefit from it. The dose for gerd is 1 mg/kg/day so if your son is 16 kg then you are giving the correct dose. You are probably aware that the expiry date is 14 days of the prilosec (45 in fridge). For prevacid it is 14 days and 28 days respectively. Over the course of a week you should have a good idea if it is going to work. If not then the dose may need to be adjusted if possible and perhaps a second drug like a motillity agent or ranitidine at bedtime may help. Like I have said before, the compounded products are not difficult to make but they are not the most stable when compounded. The solutabs have that advantage over them. Try adding one or both of the above meds.
Thanks, Graham Ph.C.