PREPARATIONS: Tablets: 10 and 20mgSTORAGE
Store at room temperature, 20-25°C (68-77°F). Keep away from moisture.
OTHER USES
Although pantoprazole is approved for the treatment of gastro
esophageal reflux disease (GERD), like other PPI's it also is used for
treating ulcers of the stomach and duodenum, and the Zollinger-Ellison
Syndrome.
PEDIATRIC DOSING
Currently not FDA approved in the treatment of children and infants.
For GERD the recommended dose for adults is 20 mg daily for 4-8 weeks.
It generally is recommended that tablets be taken approximately 30
minutes prior to meals for maximal effectiveness. Tablets should be
swallowed whole and should not be crushed, split or chewed.
DRUG INTERACTIONS
The absorption of certain drugs may be affected by stomach acidity,
and, as a result, pantoprazole and other PPI’s that reduce stomach acid
also reduce the absorption and concentration in blood of ketoconazole (Nizoral)
and increase the absorption and concentration in blood of digoxin (Lanoxin).
This may lead to reduced effectiveness of ketoconazole or increased
digoxin toxicity, respectively.
SIDE EFFECTS
Rabeprazole like other PPI’s is well-tolerated. The most common side
effects are diarrhea, nausea, vomiting, constipation, rash and headaches.
Dizziness, nervousness, abnormal heartbeat, muscle pain, weakness, leg
cramps and water retention rarely occur.
Rabeprazole may cause increased sensitivity to the sun. Avoid exposure
to the sun, sun lamps, or tanning booths until you know how you react to
Rabeprazole. Use a sunscreen or protective clothing if you must be outside
for a prolonged period. |
